Flake has made similar comments before and has said that Republicans took the wrong position when they insisted that the next president should choose a nominee to replace the late Justice Antonin Scalia.
Earlier in October, he said that Republicans don't actually believe the next president should choose the nominee and that they should have instead pushed "to confirm the most conservative justice to replace Scalia." And if Clinton is elected, that justice would be Garland, Flake told the Daily Beast at the time.
In May, Flake suggested Republicans consider confirming Garland if Clinton wins the presidency.
"If we come to a point, I've said all along, where we're going to lose the election or we lose the election in November, then we ought to approve him quickly, because I'm certain he'll be more conservative than a Hillary Clinton nomination come January," the Republican senator said on NBC's "Meet the Press."