The president called on the House to take up the bill, which looks unlikely due to Speaker John Boehner's (R-OH) opposition.
"Now it's up to the House of Representatives," Obama said. "This bill has the overwhelming support of the American people, including a majority of Republican voters, as well as many corporations, small businesses and faith communities. They recognize that our country will be more just and more prosperous when we harness the God-given talents of every individual."
White House spokesman Jay Carney said Thursday that lawmakers who don't support ENDA are on the wrong side of history.
"To oppose this legislation is to announce that you want to be left behind by history," Carney said in a press briefing.