News reports of the Ebola outbreak flash in quick succession, intercut with footage and a map of west Africa. The words "only one against pandemic response" appear above the frantic imagery.
“Tom Cotton voted against preparing America for pandemics like Ebola,” the ad says, claiming Cotton voted to cut medical disaster and emergency programs.
"Instead, Cotton voted for tax cuts for billionaires funding his campaign," a male voice says. "Rather than protecting our families," a female voice adds.
The ad isn't the only recent TV spot to veer into apocalyptic territory. The group Secure America Now this month released its "Daisy 2" ad, returning to 1960s imagery of nuclear annihilation. Meanwhile, a spot by a New Mexico GOP Senate candidate featured images of the masked militant who beheaded journalist James Foley.
Watch the Pryor ad below: