During an interview Tuesday on Phoenix radio station KFYI, McCain was asked for a Super Bowl prediction — and he made sure to take a not-so-veiled dig at Sherman.
"I think Denver," McCain told host Mike Broomhead. "You know, everybody is such a [Peyton] Manning fan and that loudmouth from Seattle sort of epitomizes the Seattle team to me. I'm sure I'm gonna get in trouble for that one, too."
McCain also took a shot at Sherman's head coach, Pete Carroll, who left his position at the University of Southern California in 2009 right before the program was sanctioned by the NCAA.
"He gets out one step ahead of the sheriff. He gets out of town," McCain said of Carroll.
After making a play that helped clinch a win over the San Francisco 49ers and secure Seattle's berth in the Super Bowl, the fiery Sherman gave an interview on Fox in which he was both boastful and disparaging.
"I'm the best cornerback in the game," Sherman screamed into the camera. "When you try me with a sorry receiver like [the 49ers Michael] Crabtree, that's the result you are going to get. Don't you ever talk about me."
Sherman later expressed regret for his comments, but not before he suggested that his harsh words were a response to something Crabtree did during an offseason function last summer in Arizona. According to the Seattle Times, Crabtree tried to fight Sherman at a charity event.
McCain relishes the opportunity to talk sports. An avid fan of Phoenix-based sports franchises, the senator unloaded on the Los Angeles Dodgers last year after the team celebrated a victory over the Arizona Diamondbacks by taking a dip in the Diamondbacks' swimming pool.
McCain made it clear to Broomhead that he hasn't gotten over the display.
"Now all we need to do is have the D-Backs beat the crap out of the Dodgers every time we play 'em," McCain said. "I will never forget them jumping in that swimming pool. I'm tellin' you: I don't hold a grudge against old political opponents, but I hold a grudge for the Dodgers jumping into that swimming pool."
"God, talk about no class. Spoiled, rich brats," he added.