Huckabee addressed the Supreme Court, which this week listened to oral arguments in its highly anticipated hearings on gay marriage.
"I respect the courts, but the Supreme Court is only that — the supreme of the courts. It is not the supreme being. It cannot overrule God," he reportedly told the audience.
"When it comes to prayer, when it comes to life, and when it comes to the sanctity of marriage, the court cannot change what God has created," Huckabee added.
A favorite of the Christian conservative crowd, Huckabee also brought up the political skirmishes on recent "religious freedom" laws in Indiana and Arkansas, saying that Christianity is becoming "criminalized."
The ex-governor added that someone must be ready to take on the institutions that "challenge and threaten our ability to believe as we believe."