As hospitals across the country face drastic shortages of masks, respirators and other vital equipment, the White House has sent out a plea for donations that’s left many recipients confused and full of questions.

In at least one instance this week, Vice President Mike Pence, who heads the Trump administration’s coronavirus task force, blindsided private industry by requesting that construction companies donate face masks to hospitals. The White House then failed to provide guidance when directly asked.

Pence asked builders on Tuesday to donate the N95 masks used at many construction sites to local hospitals and refrain from ordering more. Within minutes, Stephen Sandherr, chief executive officer of the trade group Associated General Contractors of America, contacted the White House for more details, said Brian Turmail, a group spokesman.

After receiving no reply from the White House, Sandherr sent an email to AGC’s local chapters on Tuesday telling them that Pence’s statement had taken the group by surprise.

“As we received no advance notice of this announcement and we have received no additional guidance from the Administration, it is our view that this should be considered as a voluntary gesture and not a mandate,” Sandherr wrote. Turmail said several AGC members have donated equipment to their local hospitals.

On Thursday, Sandherr finally heard back from the Department of Health and Human Services, speaking on behalf of the White House, and his group’s members were asked not to donate equipment to hospitals, as Pence had instructed. Instead, he was told the group should collect an inventory of available equipment from members, including masks, booties and protective suits, and share it with the administration.

“It isn’t clear to us, yet, how they intend to use this information, but obviously we are happy to collect the info and share it,” Turmail said.

Recently, the National Association of Manufacturers, a prominent business group, sent its members a White House request asking for “volunteers who can donate and provide and/or produce within two weeks large-scale quantities of critical supplies to help the nation respond to the COVID-19 pandemic.”

The notice — which consisted of a short questionnaire prepared through Survey Monkey — did not explain how the White House would distribute donated equipment to states demanding urgent help, including distributions from the national stockpile of emergency supplies and medications.

The problem with that strategy, said Dr. Tom Inglesby, director of the Center for Health Security of the Johns Hopkins Bloomberg School of Public Health, is that it is far too small and piecemeal to meet a demand for protective equipment that is likely to persist for months.

“Good ideas can come from everywhere, but this seems like the wrong scale of effort by orders of magnitude,” Inglesby said. He noted that producing enough masks, gloves and other supplies will require complicated analyses of shortages and manufacturing capabilities as well as negotiating new contracts and large financial commitments to incentivize businesses to retool production lines.

“That to me suggests we should have a large professional logistics organization running things in a centralized manner that can help states around the country,” Inglesby said.

Jeremy Konyndyk, a former official at the U.S. Agency for International Development who worked on the Ebola virus response, said the government’s efforts to reach out to trade associations are “not a bad idea” and would reach many potential private sector partners. But he said given how the virus is spreading, voluntary donations “will be a month out of sync with transmission.”

The donation request was circulated widely and made its way to some small businesses struggling to stay afloat as the health crisis escalates.

“I was troubled,” said Tsan Abrahamson, a California attorney who is a member of the Women’s Business Enterprise National Council, which certifies women-owned businesses. WBENC sent out a plea to members on Wednesday saying the White House had asked for donations of supplies. The WBENC email directed members to fill out the NAM questionnaire.

Abrahamson said women-owned companies are “traditionally marginalized businesses who are being asked to donate not to those in specific need, like hospitals, nursing homes, grocery stock warehouses.” Instead, the survey asks respondents for their contact information so they can be reached directly by the White House for follow-up.

The request was part of a “whole of America” approach pushed by Pence to combat the coronavirus, emphasizing robust, voluntary partnerships with the private sector.

The White House and WBENC did not respond to questions, and a NAM spokesman declined to respond to questions.

Health care workers are growing desperate for gear to protect them from airborne particles and liquids that can spread the coronavirus. The U.S. Centers for Disease Control and Prevention has downgraded its guidance for how health workers should protect themselves, saying they “might use homemade masks” like a bandanna or scarf if no masks are available.

Elizabeth Zimmerman, a former associate administrator at the Federal Emergency Management Agency, said FEMA has coordinated with the private sector to identify supply shortfalls in past emergencies, but she was not sure if that coordination included online surveys of the type sent out by NAM.

On Wednesday, Trump signed an executive order invoking the Defense Production Act, which gives the president broad authority to require companies to prioritize government contracts and incentivize companies to expand production of critical goods. The executive order granted Health and Human Services Secretary Alex Azar additional powers to allocate medical supplies.

But the president has contradicted himself several times on whether he has actually triggered the DPA. In a Thursday press conference, he said “we hope we’re not going to need that” and put the onus on individual states.

“The federal government is not supposed to be out there buying vast amounts of items and then shipping. You know, we’re not a shipping clerk,” Trump said.

Just hours later, governors on a teleconference with Trump, Pence, Azar and other senior officials complained that their efforts to get crucial supplies on the private market were floundering.

Pence said during that teleconference that although Trump had “activated” the DPA, “he has not initiated any other action underneath it” and suggested that voluntary decisions by American businesses would be sufficient to meet the critical needs.

“I think the president’s perception and the team’s perception is now” that “American industry is stepping forward very aggressively,” Pence said.

Then on Friday, in response to a question about whether Trump was using the DPA to “tell businesses they need to make ventilators, masks, respirators,” Trump nodded and said, “We are using it.”

“We are using the act, the act is very good for things like this,” Trump said. “We’re invoking it to use the powers of the federal government to help the states get things that they need, like the masks, like the ventilators.”

Minutes later, Trump appeared to backtrack, saying that “when we need something, we will use the act.”

As of Friday, Louisiana was reporting 479 confirmed cases of COVID-19, one of the highest numbers in the country. Ten people had died. The majority of cases are in New Orleans, which now has one confirmed case for every 1,000 residents. New Orleans had held Mardi Gras celebrations just two weeks before its first patient, with more than a million revelers on its streets.

I spoke to a respiratory therapist there, whose job is to ensure that patients are breathing well. He works in a medium-sized city hospital’s intensive care unit. (We are withholding his name and employer, as he fears retaliation.) Before the virus came to New Orleans, his days were pretty relaxed, nebulizing patients with asthma, adjusting oxygen tubes that run through the nose or, in the most severe cases, setting up and managing ventilators. His patients were usually older, with chronic health conditions and bad lungs.

Since last week, he’s been running ventilators for the sickest COVID-19 patients. Many are relatively young, in their 40s and 50s, and have minimal, if any, preexisting conditions in their charts. He is overwhelmed, stunned by the manifestation of the infection, both its speed and intensity. The ICU where he works has essentially become a coronavirus unit. He estimates that his hospital has admitted dozens of confirmed or presumptive coronavirus patients. About a third have ended up on ventilators.

His hospital had not prepared for this volume before the virus first appeared. One physician had tried to raise alarms, asking about negative pressure rooms and ventilators. Most staff concluded that he was overreacting. “They thought the media was overhyping it,” the respiratory therapist told me. “In retrospect, he was right to be concerned.”

He spoke to me by phone on Thursday about why, exactly, he has been so alarmed. His account has been condensed and edited for clarity.

“Reading about it in the news, I knew it was going to be bad, but we deal with the flu every year so I was thinking: Well, it’s probably not that much worse than the flu. But seeing patients with COVID-19 completely changed my perspective, and it’s a lot more frightening.”

“I have patients in their early 40s and, yeah, I was kind of shocked. I’m seeing people who look relatively healthy with a minimal health history, and they are completely wiped out, like they’ve been hit by a truck. This is knocking out what should be perfectly fit, healthy people. Patients will be on minimal support, on a little bit of oxygen, and then all of a sudden, they go into complete respiratory arrest, shut down and can’t breathe at all.”

“We have an observation unit in the hospital, and we have been admitting patients that had tested positive or are presumptive positive — these are patients that had been in contact with people who were positive. We go and check vitals on patients every four hours, and some are on a continuous cardiac monitor, so we see that their heart rate has a sudden increase or decrease, or someone goes in and sees that the patient is struggling to breathe or is unresponsive. That seems to be what happens to a lot of these patients: They suddenly become unresponsive or go into respiratory failure.”

“It’s called acute respiratory distress syndrome, ARDS. That means the lungs are filled with fluid. And it’s notable for the way the X-ray looks: The entire lung is basically whited out from fluid. Patients with ARDS are extremely difficult to oxygenate. It has a really high mortality rate, about 40%. The way to manage it is to put a patient on a ventilator. The additional pressure helps the oxygen go into the bloodstream.

“Normally, ARDS is something that happens over time as the lungs get more and more inflamed. But with this virus, it seems like it happens overnight. When you’re healthy, your lung is made up of little balloons. Like a tree is made out of a bunch of little leaves, the lung is made of little air sacs that are called the alveoli. When you breathe in, all of those little air sacs inflate, and they have capillaries in the walls, little blood vessels. The oxygen gets from the air in the lung into the blood so it can be carried around the body.

“Typically with ARDS, the lungs become inflamed. It’s like inflammation anywhere: If you have a burn on your arm, the skin around it turns red from additional blood flow. The body is sending it additional nutrients to heal. The problem is, when that happens in your lungs, fluid and extra blood starts going to the lungs. Viruses can injure cells in the walls of the alveoli, so the fluid leaks into the alveoli. A telltale sign of ARDS in an X-ray is what’s called ‘ground glass opacity,’ like an old-fashioned ground glass privacy window in a shower. And lungs look that way because fluid is white on an X-ray, so the lung looks like white ground glass, or sometimes pure white, because the lung is filled with so much fluid, displacing where the air would normally be.”

“With our coronavirus patients, once they’re on ventilators, most need about the highest settings that we can do. About 90% oxygen, and 16 of PEEP, positive end-expiratory pressure, which keeps the lung inflated. This is nearly as high as I’ve ever seen. The level we’re at means we are running out of options.

“In my experience, this severity of ARDS is usually more typical of someone who has a near drowning experience — they have a bunch of dirty water in their lungs — or people who inhale caustic gas. Especially for it to have such an acute onset like that. I’ve never seen a microorganism or an infectious process cause such acute damage to the lungs so rapidly. That was what really shocked me.”

“It first struck me how different it was when I saw my first coronavirus patient go bad. I was like, Holy shit, this is not the flu. Watching this relatively young guy, gasping for air, pink frothy secretions coming out of his tube and out of his mouth. The ventilator should have been doing the work of breathing but he was still gasping for air, moving his mouth, moving his body, struggling. We had to restrain him. With all the coronavirus patients, we’ve had to restrain them. They really hyperventilate, really struggle to breathe. When you’re in that mindstate of struggling to breathe and delirious with fever, you don’t know when someone is trying to help you, so you’ll try to rip the breathing tube out because you feel it is choking you, but you are drowning.

“When someone has an infection, I’m used to seeing the normal colors you’d associate with it: greens and yellows. The coronavirus patients with ARDS have been having a lot of secretions that are actually pink because they’re filled with blood cells that are leaking into their airways. They are essentially drowning in their own blood and fluids because their lungs are so full. So we’re constantly having to suction out the secretions every time we go into their rooms.”

“Before this, we were all joking. It’s grim humor. If you are exposed to the virus and test positive and go on quarantine, you get paid. We were all joking: I want to get the coronavirus because then I get a paid vacation from work. And once I saw these patients with it, I was like, Holy shit, I do not want to catch this and I don’t want anyone I know to catch this.

“I worked a long stretch of days last week, and I watched it go from this novelty to a serious issue. We had one or two patients at our hospital, and then five to 10 patients, and then 20 patients. Every day, the intensity kept ratcheting up. More patients, and the patients themselves are starting to get sicker and sicker. When it first started, we all had tons of equipment, tons of supplies, and as we started getting more patients, we started to run out. They had to ration supplies. At first we were trying to use one mask per patient. Then it was just: You get one mask for positive patients, another mask for everyone else. And now it’s just: You get one mask.

“I work 12-hour shifts. Right now, we are running about four times the number of ventilators than we normally have going. We have such a large volume of patients, but it’s really hard to find enough people to fill all the shifts. The caregiver-to-patient ratio has gone down, and you can’t spend as much time with each patient, you can’t adjust the vent settings as aggressively because you’re not going into the room as often. And we’re also trying to avoid going into the room as much as possible to reduce infection risk of staff and to conserve personal protective equipment.”

“But we are trying to wean down the settings on the ventilator as much as possible, because you don’t want someone to be on the ventilator longer than they need to be. Your risk of mortality increases every day that you spend on a ventilator. The high pressures from high vent settings is pushing air into the lung and can overinflate those little balloons. They can pop. It can destroy the alveoli. Even if you survive ARDS, although some damage can heal, it can also do long-lasting damage to the lungs. They can get filled up with scar tissue. ARDS can lead to cognitive decline. Some people’s muscles waste away, and it takes them a long time to recover once they come off the ventilator.

“There is a very real possibility that we might run out of ICU beds and at that point I don’t know what happens if patients get sick and need to be intubated and put on a ventilator. Is that person going to die because we don’t have the equipment to keep them alive? What if it goes on for months and dozens of people die because we don’t have the ventilators?

“Hopefully we don’t get there, but if you only have one ventilator, and you have two patients, you’re going to have to go with the one who has a higher likelihood of surviving. And I’m afraid we’ll get to that point. I’ve heard that’s happening in Italy.”