Clinton leads a head-to-head match, 47-37, against the businessman.
When third party candidates are included in the race, Clinton leads by nine points, 43-34, with Libertarian Gary Johnson polling at 7 percent and Green Party candidate Jill Stein at 2 percent.
The former Secretary of State's advantage over Trump has increased since CNBC last polled the general election in June. At that time, she led by five points in a head-to-head match, an advantage she's doubled to 10 points today.
Recent polls show her with similar leads over Trump. Among the national polls released Wednesday, Clinton led +13 in an AP/GfK poll, +10 in a Suffolk University/USA Today poll, and +5 in a Fox News poll.
The CNBC poll was conducted in a joint effort by Democratic pollster Hart Research and Republican pollster Public Opinion Strategies. The poll surveyed 804 likely voters nationwide and has a margin of error of plus or minus 3.5 percent.
TPM's PollTracker Average for the general election shows Clinton leading Trump, 49.1 to 40.3.