As he delivered his address to a room largely filled with those who oppose his views, about 2,000 gathered at the school's football stadium nearby protesting his message, according to the Dallas Morning News.
Two protesters who were not students were arrested, according to Texas A&M university police.
The school's chancellor, John Sharp, addressed the protesters and reaffirmed that Texas A&M does not support Spencer's message.
"If you’re a purveyor of hate and divisiveness and you want to spew that kind of racism, this is the last campus on earth that you want to come to," he said, according to the Dallas Morning News. "There is no place, and there is no university where love and respect for each other and loyalty and commitment to each other is stronger than Texas A&M University."
Protesters also gathered in the student center where Spencer was speaking, according to the Bryan-College Station Eagle. Before the speech ended, police ordered the protesters to leave the area and one woman who refused to leave was taken away in handcuffs, according to the Eagle.
Spencer recently gave a speech in Washington, D.C. at a white nationalist conference where he said that white people were "awakening to their own identity" under Donald Trump. At the end of his speech, Spencer said, "Hail Trump, hail our people, hail victory!"