"You lost!" Scarborough exclaimed. "When you lose, you lose because you're too stupid to use tactics to adjust."
Cochran eked out a narrow victory in Tuesday's runoff in part because his campaign courted black and Democratic voters to support him in the open election. McDaniel refused to concede the race after it was called for Cochran, however, and cited "irregularities" in voting when he vowed to fight the election results.
McDaniel also got some backup Wednesday from Sarah Palin, who called for an investigation into whether any illegal activity took place in the runoff election.
"I can tell you if these people were my children, I would be laughing at them calling them the biggest whiners," Scarborough said. "'They cheated!' No, they didn't, they followed the rules. They followed the law."
The MSNBC host hailed Cochran's campaign for making progress toward getting black voters to cross over and vote Republican.
"This is actually positive. We're expanding the brand," he said. "We got a large number of African-Americans to do what a large number of African-Americans haven't wanted to do, for good reason, over the past 30, 40, 50 years -- vote in Republican primaries. These whiners are the past. They lost."