Warren jumps ahead of Brown in new Massachusetts Senate poll. 49%-42%.

The poll has a relatively small sample size: 505 registered voters. But it’s a 10 point swing from the last time this pollster (UMass-Lowell/Princeton Survey Research) sampled this race. And it’s in line with the trend in Warren’s direction.

Just as importantly, this race is crystallizing the core issues the 2012 cycle looks set to turn on — finance vs. main street, wealth and income inequality, the pros and cons of survival of the fittest economics.

If Warren can get traction against Brown with her unalloyed version of this message, that will cast a shadow over as yet unformed races across the nation.