Clinton leads the poll of likely voters, 49-38, with Libertarian Gary Johnson polling at 4 percent and Green Party candidate Jill Stein at 2 percent.
The former Secretary of State expanded her lead by a two points since Franklin & Marshall last polled the state in September, when Clinton led 47-38.
However her lead in the latest Franklin & Marshall poll is larger than recent Pennsylvania polls, which show a slightly closer race.
The Franklin & Marshall poll was conducted Oct. 26-30 over the phone and online among 652 likely Pennsylvania voters, with a margin of error of plus or minus 5.1 percent.
TPM's PollTracker Average for the general election in Pennsylvania shows Clinton leading Trump, 47.1 to 41.9.