The poll, conducted days after the release of a video showing Trump's offense comments about women, shows Clinton ahead by five points, 46-41, with Libertarian Gary Johnson at 6 percent and Green Party candidate Jill Stein at 2 percent.
This new poll shows an improvement nationally for Clinton, who led by just two points when Franklin Pierce University/Boston Herald conducted a national election poll in September.
In that previous survey, Clinton led 45-43, with Johnson at 6 percent and Stein at 2 percent.
The Franklin Pierce University/Boston Herald poll was conducted Oct. 9-13 among 1,011 likely voters nationwide, with a margin of error of plus or minus 3.1 percent.
TPM's PollTracker Average for the general election shows Clinton leading Trump, 44.7 to 42.