"The global war on drugs has failed, with devastating consequences for individuals and societies around the world," the report reads. "Fifty years after the initiation of the UN Single Convention on Narcotic Drugs, and 40 years after President Nixon launched the US government's war on drugs, fundamental reforms in national and global drug control policies are urgently needed."
Among the members of the commission are former presidents of Columbia, Mexico and Brazil, former UN Secretary General Kofi Annan, former U.S. Secretary of State George P. Shultz and former Fed Chair Paul Volcker, among others.
The report calls for an end to the "criminalization, marginalization and stigmatization of people who use drugs but who do no harm to others," and for governments to experiment with ways to regulate drugs so as to undercut organized crime and improve public health.
"Begin the transformation of the global drug prohibition regime," the report says. "Replace drug policies and strategies driven by ideology and political convenience with fiscally responsible policies and strategies grounded in science, health, security and human rights - and adopt appropriate criteria for their evaluation."
Read the full report here.
In a comment to The Guardian, a spokesman for White House drug tsar Gil Kerlikowske disagreed with the report's conclusions.
"Drug addiction is a disease that can be successfully prevented and treated. Making drugs more available - as this report suggests - will make it harder to keep our communities healthy and safe," the spokesman said.