Rep. Elijah Cummings (D-MD), ranking member of the Oversight Committee, butted in as Issa was being questioned by Rep. Jared Polis (D-CO).
"We are now about to find in contempt the attorney general of the United States of America after you just heard that," Cummings said.
"Sure," replied Issa. "It's not for what the attorney general knew about Fast and Furious, it's about the attorney general's refusal to provide the documents."
Issa's position on Holder's knowledge of the tactics used is a reversal of what he claimed when he began his investigation last year, when he said the tactics went "all the way to the very top." The California Republican has admitted to exploring "blind alleys" over the course of the investigation.
The House is set to vote on a resolution finding Holder in contempt tomorrow. The resolution focuses on DOJ's opposition to disclosing internal Justice Department communications created after Feb. 4, 2011 unless Issa agrees to let that disclosure settle his subpoena.
Late update: House Democrats posted video of the exchange.