Pelosi called the employer mandate "integral" to the law on CNN's "State of the Union" when asked by anchor Candy Crowley if the component would ever be repealed.
"This is an initiative that has strong pillars in it that relate to each other," she said.
"No. I don't know why we're focusing on that. One person says one thing," Pelosi added when Crowley pressed her again about whether the business mandate would say.
Pelosi also suggested that Gibb's comments stemmed not from his knowledge of the law, but his current interests now that he has left the White House.
"I don't know who his clients are or what his perspective is," she said when first asked about his prediction. "But we are celebrating the fact that we have over seven million who have signed up."
Watch the video via CNN: