Former Sen. John Sununu (R-NH) has announced that he will not run for the open Senate seat of retiring GOP incumbent Judd Gregg.
Sununu lost his seat in the 2008 Democratic landslide to Democratic former Gov. Jeanne Shaheen, a rematch from his previous victory over her in the Republican year of 2002. New Hampshire has very much realigned to the Democrats in a lot of ways since then, and Sununu was swept out along the way.
The presumptive Democratic nominee for the open seat in 2010 will be Rep. Paul Hodes. The Republicans do not yet have a candidate, though a lot of people were waiting on word from Sununu first. This appears to be leaning towards a Democratic pickup, but the cycle has obviously just begun.