"We take nothing for granted," Nancy Keenan, president of NARAL Pro-Choice America, told TPM. "Especially when you take a look at the composition of the court right now, and when you take a look at when people might retire from the court. It is something that is always on our minds, and that's why we work so diligently to elect pro-choice candidates, in the Oval Office or in the United States Senate."
All of the Republican 2012 candidates, she added, are "absolutely" a threat to Roe v. Wade.
The pro-choice community sees Justices Antonin Scalia, Clarence Thomas, John Roberts and Samuel Alito as dangerous to their cause, Keenan said. Justice Anthony Kennedy is currently seen as the swing vote as he has a mixed record on abortion cases. And two of the high court's strong supporters of abortion rights -- Justices Ruth Bader Ginsburg and Stephen Breyer -- are 78 and 73, respectively.
Scalia in particular has been hypercritical of abortion rights laws and has persistently called on colleagues to overturn Roe v. Wade, which he says was improperly decided.
A Republican president would be all but certain, if given the chance, to appoint justices who are hostile to abortion rights. And the math favors the GOP to take back the Senate in 2012, which could help get those justices confirmed.
"Despite the fact that there is mainstream, bipartisan consensus on upholding Roe v. Wade, the leading GOP presidential candidates have pledged to appoint judges that would overturn Roe v. Wade," Tait Sye, spokesperson for Planned Parenthood, told TPM.
The Supreme Court's anti-abortion turn was widely noted after a 2007 case when Alito, who replaced Justice Sandra Day O'Connor the year before, became the fifth vote to outlaw what pro-lifers call partial birth abortions. The decision reversed a 5-4 ruling in 2000 -- which O'Connor voted on the winning side of -- that struck down a Nebraska law criminalizing that type of procedure.
"Alito replaced O'Connor and that was the deciding factor," Keenan said. "That is the consequence of putting people in the Supreme Court who don't share our values."
For now, the prospect of Roe v. Wade being overturned is just one of many concerns for pro-choice advocates. The Republican resurgence of 2010 saw widespread anti-abortion legislation pass in various states last year -- along with a congressional GOP push to scale back abortion nationally. Keenan and Planned Parenthood president Cecile Richards each dubbed 2011 the year of the "war on women."