The Financial Times reports that some cases in the San Francisco U.S. Attorney's office are moving so slowly that the Securities and Exchange Commission is considering moving forward with its civil cases alone rather than waiting on the Justice Department, with whom the SEC usually jointly files cases:

The San Francisco slowdown is the most dramatic example of larger problems that have surfaced at the DoJ since the mass sackings of eight US attorneys, including Mr [Kevin] Ryan, caused a furore in February. Six top posts at the DoJ in Washington are empty or filled with temporary appointees, and 23 of the 93 US Attorney’s offices around the country lack permanent political leadership.

Frankly, I wouldn't call this the "most dramatic example" of the problems at DOJ. The politicization at all levels that has emerged since the USAs purge is far more dramatic and more serious. But the FT report does show how even the routine work of the department is being disrupted by the dreadful leadership of Alberto Gonzales.